Functions · Pharmacovigilance

Pharmacovigilance & Drug Safety

Put a safety signal in context across the class: who is running what, which populations are enrolled, and which trials stopped.

11ranked use cases
#38highest overall rank: Signal detection context
1 clickfrom recipe to a board with the right charts
Lead chart, on real data

What this team sees first.

A Sankey flow shows where trials end up by sponsor type. In Phase 3 atopic dermatitis, 23 of 245 industry trials stopped.

Every use case below opens with its signature chart and a recommended set of supporting views, chosen from 91 chart types.

Built for: Pharmacovigilance Signal Lead, PV, Drug Safety, Benefit-Risk, Pharmacovigilance.

Sankey · sponsor class → statusReal data

Industry runs 245 of 278 Phase 3 atopic dermatitis trials; 23 of those stopped

ClinicalTrials.gov API, pulled 16 Oct 2026: interventional Phase 3 atopic dermatitis trials, all years. Stopped = terminated, withdrawn or suspended. Government includes NIH, federal, other government, networks and individual investigators.

The 11 questions

Ranked by stakes, centrality, reach, frequency and data fit.

Each use case ships with an executive brief, a detailed dossier and a recipe that builds the board in one click.

  • PV-01
    #38

    Signal detection context

    Check whether an adverse event has been observed in related programs across the compound class.

    For: Pharmacovigilance Signal Lead
    Forest plotAnalysis of Competing Hypotheses matrixKPI / metric snapshot panel
  • PV-02
    #48

    Periodic safety update report (PSUR) support

    Compile a complete list of studies using your compound or class for the PSUR clinical overview.

    For: PV / Aggregate Reporting Lead
    Composition / share-of-inventory chartForest plotKPI / metric snapshot panel
  • PV-03
    #49

    Safety population benchmarking

    Understand what populations are typically enrolled to inform your expected safety profile.

    For: Drug Safety / PV Scientist
    Forest plotComposition / share-of-inventory chartHeatmap / matrix
  • PV-11N
    #50

    MedDRA-harmonised class safety landscape

    A normalised, class-wide safety view across trials and labels using MedDRA and ATC coding.

    For: Pharmacovigilance Signal Lead
    Bullseye100% stacked barComposition / share-of-inventory chart
  • PV-04
    #71

    Benefit-risk framework enrichment

    Quantify total patient exposure across an indication to support the benefit-risk narrative.

    For: Benefit-Risk / PV Lead
    Composition / share-of-inventory chartForest plotHeatmap / matrix
  • PV-05
    #72

    Background incidence rate research

    Find studies measuring disease natural history and event rates for adverse-event context.

    For: Pharmacovigilance / Epidemiology Lead
    Forest plotComposition / share-of-inventory chartHeatmap / matrix
  • PV-06
    #84

    Patient sub-population risk monitoring

    Identify trials studying vulnerable populations in your class to inform safety monitoring.

    For: Drug Safety / PV Scientist
    TimelineProbability-impact bubble chartComposition / share-of-inventory chart
  • PV-07
    #86

    Long-term follow-up study identification

    Find long-term extension/follow-up studies offering durability and late-onset safety data.

    For: PV / Long-Term Safety Lead
    Composition / share-of-inventory chartForest plotTimeline
  • PV-08
    #88

    Risk minimization measure benchmarking

    See what risk-minimization measures regulators have already required for comparable products.

    For: Drug Safety / RMP Lead
    Feature-by-feature alignment chartComposition / share-of-inventory chartForest plot
  • PV-09
    #89

    Post-authorization safety study (PASS) design

    Find existing PASS-style designs to use as templates or to identify collaborating sites.

    For: PV / RWE Study Lead
    Composition / share-of-inventory chartForest plotPoint / site map with catchment radii
  • PV-10
    #90

    Expedited reporting threshold calibration

    Understand what events have triggered early study stops to calibrate reporting thresholds.

    For: PV / Risk Lead
    KPI / metric snapshot panelComposition / share-of-inventory chartForest plot
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